Engineering the cure for autoimmune diseases

RheumaGen is developing a breakthrough class of cell and gene therapies designed to cure autoimmune diseases at their source. The company is focused on editing the human leukocyte antigen (HLA), or “immune gene,” so that the immune system does not attack healthy cells.

Transformative Therapeutic Approach

RheumaGen is pioneering the first one-time, curative cell and gene therapies for refractory or treatment-resistant rheumatoid arthritis (RA) and other autoimmune diseases, such as progressive forms of multiple sclerosis, type 1 diabetes, and ankylosing spondylitis.

RheumaGen was founded to relieve the burden that individuals suffering from autoimmune diseases have carried for so long. Mindful also of our own family members who are patients, we are not interested in incremental improvements. We seek cures; we seek remission.

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Oct 28, 2025

RheumaGen Presents HLA Gene-Editing Preclinical Data for Nearly Universal Autoimmune Disease Target at...

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Oct 8, 2025

RheumaGen Recognized by the Colorado BioScience Association as a Rising Star of the...

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Oct 7, 2025

RheumaGen and SiVEC Biotechnologies Announce CGT Partnership and In Vivo Program to Cure...

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